CD8A Monoclonal Antibody,PE-Cy5 Conjugated
Catalogue Number: CSB-MA985168-CSB
| Manufacturer: | Cusabio Biotech |
| Preservative: | 0.09% Sodium azide |
| Ph: | 7.4 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | |
| Isotype: | IgG1 |
| Immunogen: | Recombinant Protein |
| Application: | ELISA, FC, IF |
Description
Description: COV8 reacts with the 32 kDa a chain of CD8. This molecule is expressed on the T suppressor/cytotoxic cell population (which comprises about 1/3 of the peripheral blood T lymphocytes total population) and with most of thymocytes, as well as a subset of NK cells. CD8 expresses as either a heterodimer with the CD8b chain (CD8ab) or as a homodimer (CD8aa or CD8bb). CD8 acts as a co-receptor with MHC Class I restricted TCRs in antigen recognition. CD8 function is important for positive selection of MHC Class I restricted CD8+ T cells during T cell development.* Ratio of CD4 and CD8 is important for monitor of HIV infection.1. Engleman EG et al. (1981) J Exp Med 153: 193-198.2. Haynes, B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.3. Parnes, JR. et al. (1989). Adv. Immunol. 44,256-311.4. Bikah G. et al. (1996). Science 274:1906.
Additional Text
Gene ID
925
Gene Name
CD8A
Uniprot ID
P01732
Purification
Affinity Purified
Antibody Clonality
Monoclonal
CSB-MA985168 Datasheet
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