Recombinant Human Monocyte differentiation antigen CD14(CD14)
Catalogue Number: CSB-MP004879HU-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 39.2 kDa |
| Physical state: | Liquid or Lyophilized powder |
| Type: | Glycoproteins |
| Alias: | Myeloid cell-specific leucine-rich glycoprotein; CD14 |
| Host Cell: | Mammalian Cells |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug, 500 ug |
Description
Description: In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
Additional Text
Uniprot ID
P08571
OMIN ID
158120
Protein Tag
6xHIS-Myc Tag
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations