Recombinant Human Polypyrimidine tract-binding protein 1(PTBP1)
Catalogue Number: CSB-MP018948HU-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 63.1 kDa |
| Physical state: | Liquid or Lyophilized powder |
| Type: | Fusion Protein |
| Alias: | 57 kDa RNA-binding protein PPTB-1 (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) (PTB) (PTB) |
| Host Cell: | Mammalian Cells |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug, 500 ug |
Description
Description: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornaviruses, binds to the viral internal ribosome entry site and stimulates the IRES-mediated translation.
Additional Text
Uniprot ID
P26599
OMIN ID
600693
Protein Tag
10xHIS Tag
CSB-MP018948HU Protocol
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