Recombinant Rabbit Histidine triad nucleotide-binding protein 1 (HINT1)

Catalogue Number: CSB-MP301425RB-CSB

Manufacturer:	Cusabio Biotech
Shelf Life:	6 months
Molecular Weight:	17.6 kDa
Physical state:	Liquid or Lyophilized powder
Type:	Proteases
Alias:	Adenosine 5'-monophosphoramidase P13.7
Host Cell:	Mammalian Cells
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 20 ug, 1 mg
Host name:
Clone:
Isotype:
Immunogen:

Overview
Datasheets

Description

Description: Functions as enzyme, and as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex (By similarity). Hydrolyzes purine nucleotide phosphoramidates, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide.

Additional Text

Gene Name

HINT1

Uniprot ID

P80912

Gene ID

100009302

Protein Tag

10xHIS Tag, Myc Tag

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

CSB-MP301425RB MSDS

Price

£1,059.00

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