Recombinant Severe acute respiratory syndrome coronavirus 2 Spike glycoprotein (S) (G75V,T76I,SYLTPGD247-253del,L452Q,F490S,D614G,T859N), partial

Catalogue Number: CSB-MP3324GMY(M7)-CSB

Manufacturer:Cusabio Biotech
Shelf Life:6 months
Molecular Weight:78.9 kDa
Physical state:Liquid or Lyophilized powder
Type:Spike Proteins
Alias:(S glycoprotein)(Peplomer protein)(Spike protein S1)(Spike protein S2)
Host Cell:Mammalian Cells
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug, 1 mg

Description

Description: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein. Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry. Can be alternatively processed by host furin. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.

Additional Text

Gene Name

S

Protein Tag

10xHIS Tag, FLAG™ Tag

Gene ID

43740568

Uniprot ID

P0DTC2

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Price
£433.00


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