Catalogue Number: CSB-MP733578HU-CSB
Manufacturer: | Cusabio Biotech |
Shelf Life: | 6 months |
Molecular Weight: | 53.4 kDa |
Physical state: | Lyophilized |
Type: | Bioactive Proteins |
Alias: | 4Ig-B7-H3 (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD276) |
Host Cell: | Mammalian Cells |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug, 20 ug, 1 mg |
Description: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
CD276
80381
Q5ZPR3
hFc-Myc Tag
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.