Recombinant Human B- and T-lymphocyte attenuator (BTLA), partial (Active)
Catalogue Number: CSB-MP773799HU-CSB
CSB-MP773799HU Image
CSB-MP773799HU Image
CSB-MP773799HU Image
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
CSB-MP773799HU Image
1Measured by its binding ability in a functional ELISA. Immobilized BTLA at 5 µg/ml can bind biotinylated human TNFRSF14 (CSB-MP842173HU-A), the EC50 is 137.8-233.4 ng/ml.
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 43.9 kDa |
| Physical state: | Lyophilized |
| Type: | Bioactive Proteins |
| Alias: | (B- and T-lymphocyte-associated protein)(CD272) |
| Host Cell: | Mammalian Cells |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug, 1 mg |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: |
Description
Description: Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044).
Additional Text
Gene ID
151888
Gene Name
BTLA
Uniprot ID
Q7Z6A9
Protein Tag
hFc-Myc Tag
Storage Note
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
CSB-MP773799HU MSDS
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