CLASP2 Antibody
Catalogue Number: CSB-PA005472LA01HU-CSB
CSB-PA005472LA01HU Image
CSB-PA005472LA01HU Image
CSB-PA005472LA01HU Image
CSB-PA005472LA01HU Image
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA005472LA01HU at dilution of 1:100
CSB-PA005472LA01HU Image
Immunoprecipitating CLASP2 in HEK293 whole cell lysate Lane 1: Rabbit control IgG instead of CSB-PA005472LA01HU in HEK293 whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000) Lane 2: CSB-PA005472LA01HU (8µg) + HEK293 whole cell lysate (500µg) Lane 3: HEK293 whole cell lysate (10µg)
CSB-PA005472LA01HU Image
Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA005472LA01HU at dilution of 1:100
| Manufacturer: | Cusabio Biotech |
| Preservative: | 0.03% ProClin™ 300 |
| Ph: | 7.4 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant Human CLIP-associating protein 2 protein (226-381AA) |
| Application: | ELISA, IP, IHC |
Description
Description: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
Additional Text
Gene Name
CLASP2
Gene ID
23122
Uniprot ID
O75122
Purification
Protein G purified
Storage Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Antibody Clonality
Polyclonal
Specificity
CLAP2_HUMAN antibody; CLASP 2 antibody; Clasp2 antibody; CLIP associating protein 2 antibody; CLIP-associating protein 2 antibody; Cytoplasmic linker associated protein 2 antibody; Cytoplasmic linker-associated protein 2 antibody; hOrbit2 antibody; KIAA0627 antibody; Multiple asters (Mast) like homolog 2 antibody; Protein Orbit homolog 2 antibody
CSB-PA005472LA01HU Datasheet
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations