CLTC Antibody, FITC conjugated

Catalogue Number: CSB-PA005593LC01HU-CSB

Manufacturer:Cusabio Biotech
Preservative:0.03% ProClin™ 300
Physical state:Liquid
Type:Polyclonal Primary Antibody - Conjugated
Alias:Clathrin heavy chain 1 (Clathrin heavy chain on chromosome 17) (CLH-17), CLTC, CLH17 CLTCL2 KIAA0034
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant Human Clathrin heavy chain 1 protein (851-990aa)

Description

Description: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge (PubMed:15858577, PubMed:16968737, PubMed:21297582). The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Plays a role in early autophagosome formation (PubMed:20639872).

Additional Text

Gene Name

CLTC

Uniprot ID

Q00610

Purification

Protein G purified

Gene ID

1213

Storage Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antibody Clonality

Polyclonal