CXCR4 Antibody

Catalogue Number: CSB-PA006254YA01HU-CSB

Manufacturer:Cusabio Biotech
Preservative:0.03% ProClin™ 300
Ph:7.4
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug, 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant Human C-X-C chemokine receptor type 4 protein (1-356AA)
Application: ELISA, IF, WB, IHC

Description

Description: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

Additional Text

Gene Name

CXCR4

Uniprot ID

P61073

Gene ID

7852

Purification

Protein G purified

Antibody Clonality

Polyclonal

Specificity

C-X-C chemokine receptor type 4 antibody; CD184 antibody; CD184 antigen antibody; Chemokine (C X C motif) receptor 4 antibody; Chemokine CXC Motif Receptor 4 antibody; CXC-R4 antibody; CXCR-4 antibody; CXCR4 antibody; CXCR4_HUMAN antibody; D2S201E antibody; FB22 antibody; Fusin antibody; HM89 antibody; HSY3RR antibody; LAP 3 antibody; LAP3 antibody; LCR1 antibody; LESTR antibody; Leukocyte derived seven transmembrane domain receptor antibody; Leukocyte-derived seven transmembrane domain receptor antibody; Lipopolysaccharide associated protein 3 antibody; Neuropeptide Y receptor Y3 antibody; NPY3R antibody; NPYR antibody; NPYRL antibody; NPYY3 antibody; NPYY3R antibody; Probable G protein coupled receptor lcr1 homolog antibody; SDF 1 receptor antibody; SDF-1 receptor antibody; SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR antibody; Stromal cell derived factor 1 receptor antibody; Stromal cell-derived factor 1 receptor antibody; WHIM antibody; WHIMS antibody