NRP1 Antibody
Catalogue Number: CSB-PA016091ESR1HU-CSB
CSB-PA016091ESR1HU Image
CSB-PA016091ESR1HU Image
CSB-PA016091ESR1HU Image
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA016091ESR1HU at dilution of 1:100
CSB-PA016091ESR1HU Image
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA016091ESR1HU at dilution of 1:100
| Manufacturer: | Cusabio Biotech |
| Preservative: | 0.02% Sodium azide |
| Ph: | 7.3 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant Human Neuropilin-1 protein (684-923AA) |
| Application: | ELISA, IHC |
Description
Description: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.
Additional Text
Gene Name
NRP1
Uniprot ID
O14786
Gene ID
8829
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Specificity
A5 protein antibody; BDCA4 antibody; BLOOD DENDRITIC CELL ANTIGEN 4 antibody; CD304 antibody; Neuropilin-1 antibody; Neuropilin1 antibody; NP1 antibody; NPN1 antibody; NRP 1 antibody; NRP antibody; NRP1 antibody; NRP1_HUMAN antibody; transmembrane receptor antibody; Vascular endothelial cell growth factor 165 receptor antibody; VEGF165R antibody
CSB-PA016091ESR1HU Datasheet
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