TNF Antibody

Catalogue Number: CSB-PA147864-CSB

Manufacturer:Cusabio Biotech
Preservative:0.02% Sodium azide
Ph:7.4
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthesized peptide derived from internal of Human TNFA.
Application: ELISA, IF, IHC

Description

Description: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells. Neville M.J., J. Immunol. 162:4745-4754(1999). Xie T., Genome Res. 13:2621-2636(2003). Kim Y.J., Hum. Mol. Genet. 12:2541-2546(2003).

Additional Text

Gene Name

TNF

Gene ID

7124

Uniprot ID

P01375

Purification

Affinity Purified

Storage Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antibody Clonality

Polyclonal

Specificity

APC1 antibody; APC1 protein antibody; Cachectin antibody; DIF antibody; Differentiation inducing factor antibody; Macrophage cytotoxic factor antibody; Tnf antibody; TNF superfamily member 2 antibody; TNF superfamily, member 2 antibody; TNF, macrophage derived antibody; TNF, monocyte derived antibody; TNF-a antibody; TNF-alpha antibody; TNFA antibody; TNFA_HUMAN antibody; TNFSF2 antibody; Tumor necrosis factor (TNF superfamily member 2) antibody; Tumor necrosis factor alpha antibody; Tumor necrosis factor antibody; Tumor necrosis factor ligand superfamily member 2 antibody; Tumor Necrosis Factor, Membrane Form antibody; Tumor necrosis factor, soluble form antibody