Catalogue Number: CSB-PA273037-CSB
| Manufacturer: | Cusabio Biotech |
| Preservative: | 0.02% Sodium azide |
| Ph: | 7.4 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | CUX1 antibody; CUTL1Homeobox protein cut-like 1 antibody; CCAAT displacement protein antibody; CDP antibody; Homeobox protein cux-1 antibody |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthesized peptide derived from N-terminal of Human CUTL1. |
| Application: | ELISA, WB |
Description: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator By similarity. Neufeld E.J., Nat. Genet. 1:50-55(1992). Gloeckner G., Genome Res. 8:1060-1073(1998). Rong Zeng W., Gene 241:75-85(2000).
CUX1
P39880
1523
Affinity Purified
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Polyclonal