CUX1 Antibody

Catalogue Number: CSB-PA273037-CSB

Manufacturer:Cusabio Biotech
Preservative:0.02% Sodium azide
Ph:7.4
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:CUX1 antibody; CUTL1Homeobox protein cut-like 1 antibody; CCAAT displacement protein antibody; CDP antibody; Homeobox protein cux-1 antibody
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthesized peptide derived from N-terminal of Human CUTL1.
Application: ELISA, WB

Description

Description: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator By similarity. Neufeld E.J., Nat. Genet. 1:50-55(1992). Gloeckner G., Genome Res. 8:1060-1073(1998). Rong Zeng W., Gene 241:75-85(2000).

Additional Text

Gene Name

CUX1

Uniprot ID

P39880

Gene ID

1523

Purification

Affinity Purified

Storage Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antibody Clonality

Polyclonal