CDKN2A Antibody
Catalogue Number: CSB-PA445592-CSB
CSB-PA445592 image
CSB-PA445592 image
CSB-PA445592 Image
CSB-PA445592 Image
CSB-PA445592 image
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA233193(CDKN2A Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
CSB-PA445592 image
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA233193(CDKN2A Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
CSB-PA445592 Image
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA445592(CDKN2A Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200)
CSB-PA445592 Image
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA445592(CDKN2A Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200)
| Manufacturer: | Cusabio Biotech |
| Preservative: | 0.05% Sodium azide |
| Ph: | 7.4 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide of Human CDKN2A |
| Application: | ELISA, IHC |
Description
Description: This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53.
Additional Text
Gene Name
CDKN2A
Gene ID
1029
Uniprot ID
P42771
Purification
Affinity Purified
Storage Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Antibody Clonality
Polyclonal
Specificity
CDKN2A antibody; CDKN2 antibody; MTS1 antibody; Cyclin-dependent kinase inhibitor 2A antibody; Cyclin-dependent kinase 4 inhibitor A antibody; CDK4I antibody; Multiple tumor suppressor 1 antibody; MTS-1 antibody; p16-INK4a antibody; p16-INK4 antibody; p16INK4A antibody
CSB-PA445592 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations