HIF1AN Antibody
Catalogue Number: CSB-PA447962-CSB
CSB-PA447962 image
CSB-PA447962 image
CSB-PA447962 Image
CSB-PA447962 Image
CSB-PA447962 Image
CSB-PA447962 image
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA247101(FLG Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
CSB-PA447962 image
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA247101(FLG Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
CSB-PA447962 Image
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA447962(HIF1AN Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
CSB-PA447962 Image
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA447962(HIF1AN Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
CSB-PA447962 Image
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: 231 cells, Primary antibody: CSB-PA447962(HIF1AN Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
| Manufacturer: | Cusabio Biotech |
| Preservative: | 0.05% Sodium azide |
| Ph: | 7.4 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide of Human HIF1AN |
| Application: | ELISA, WB, IHC |
Description
Description: Hypoxia-inducible factor 1-alpha inhibitor is a protein that in humans is encoded by the HIF1AN gene. Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins
Additional Text
Gene Name
HIF1AN
Uniprot ID
Q9NWT6
Gene ID
55662
Purification
Affinity Purified
Storage Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Antibody Clonality
Polyclonal
Specificity
DKFZp762F1811 antibody; Factor inhibiting HIF-1 antibody; Factor inhibiting HIF1 antibody; FIH 1 antibody; FIH-1 antibody; FIH1 antibody; FLJ20615 antibody; FLJ22027 antibody; HIF1AN antibody; HIF1N_HUMAN antibody; Hypoxia inducible factor 1 alpha inhibitor antibody; Hypoxia inducible factor 1 alpha subunit inhibitor antibody; Hypoxia inducible factor asparagine hydroxylase antibody; Hypoxia-inducible factor 1-alpha inhibitor antibody; Hypoxia-inducible factor asparagine hydroxylase antibody; Peptide aspartate beta dioxygenase antibody
CSB-PA447962 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations