NOTCH3 Antibody
Catalogue Number: CSB-PA586591-CSB
CSB-PA586591 image
CSB-PA586591 image
CSB-PA586591 Image
CSB-PA586591 Image
CSB-PA586591 image
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA446675(NOTCH4 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
CSB-PA586591 image
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human liver cancer tissue, Human kidney tissue, Primary antibody: CSB-PA446675(NOTCH4 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
CSB-PA586591 Image
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA586591(NOTCH3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
CSB-PA586591 Image
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Human colon cancer tissue, Primary antibody: CSB-PA586591(NOTCH3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
| Manufacturer: | Cusabio Biotech |
| Preservative: | 0.05% Sodium azide |
| Ph: | 7.4 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | CADASIL antibody; CASIL antibody; NOTC3_HUMAN antibody; Notch 3 antibody; Notch 3 intracellular domain antibody; Notch homolog 3 antibody; Notch3 antibody |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide of Human NOTCH3 |
| Application: | ELISA, WB, IHC |
Description
Description: This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Additional Text
Gene Name
NOTCH3
Uniprot ID
Q9UM47
Purification
Affinity Purified
Gene ID
4854
Storage Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Antibody Clonality
Polyclonal
CSB-PA586591 Datasheet
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