KCNJ12 Antibody, Biotin conjugated

Catalogue Number: CSB-PA619877LD01HU-CSB

Manufacturer:Cusabio Biotech
Preservative:0.03% ProClin™ 300
Physical state:Liquid
Type:Polyclonal Primary Antibody - Conjugated
Alias:ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12), KCNJ12, IRK2 KCNJN1
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant Human ATP-sensitive inward rectifier potassium channel 12 protein (182-433aa)
Application: ELISA

Description

Description: Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Additional Text

Gene Name

KCNJ12

Uniprot ID

Q14500

Purification

Protein G purified

Gene ID

3768

Storage Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antibody Clonality

Polyclonal