WDR34 Antibody, Biotin conjugated

Catalogue Number: CSB-PA842668LD01HU-CSB

Manufacturer:Cusabio Biotech
Preservative:0.03% ProClin™ 300
Ph:7.4
Physical state:Liquid
Type:Polyclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug, 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant Human WD repeat-containing protein 34 protein (1-210AA)
Application: ELISA

Description

Description: Critical for ciliary functions, essential to normal development and survival, most probably as a previously unrecognized component of the mammalian dynein-motor-based intraflagellar transport (IFT) machinery. Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at 'Thr-184' and 'Thr-187' upon Il-1 beta stimulation.

Additional Text

Uniprot ID

Q96EX3

Purification

Affinity Purified

Gene ID

89891

Storage Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antibody Clonality

Polyclonal

Gene Name

DYNC2I2

Specificity

bA216B9.3 antibody; DIC5 antibody; MGC20486 antibody; OTTHUMP00000022282 antibody; RP11 216B9.5 antibody; WD repeat containing protein 34 antibody; WD repeat domain 34 antibody; WD repeat-containing protein 34 antibody; WDR 34 antibody; Wdr34 antibody; WDR34_HUMAN antibody