CHAC1 Antibody, Biotin conjugated
Catalogue Number: CSB-PA883606LD01HU-CSB
| Manufacturer: | Cusabio Biotech |
| Preservative: | 0.03% ProClin™ 300 |
| Ph: | 7.4 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant Human Glutathione-specific gamma-glutamylcyclotransferase 1 protein (43-264AA) |
| Application: | ELISA |
Description
Description: Catalyzes the cleavage glutathione into 5-oxoproline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. Glutathione depletion is an important factor for apoptosis initiation and execution (PubMed:23070364). Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade (PubMed:19109178). Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos (PubMed:22445366).
Additional Text
Gene ID
79094
Uniprot ID
Q9BUX1
Purification
Protein G purified
Gene Name
CHAC1
Storage Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Antibody Clonality
Polyclonal
Specificity
Blocks Notch protein antibody; Botch antibody; Cation transport regulator like protein 1 antibody; Cation transport regulator-like protein 1 antibody; ChaC antibody; ChaC cation transport regulator homolog 1 antibody; ChaC cation transport regulator like 1 antibody; chac1 antibody; CHAC1_HUMAN antibody; Gamma GCT acting on glutathione homolog 1 antibody; Gamma-GCG 1 antibody; Glutathione-specific gamma-glutamylcyclotransferase 1 antibody
CSB-PA883606LD01HU Datasheet
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