RAB23 Antibody
Catalogue Number: CSB-PA891960LA01HU-CSB
CSB-PA891960LA01HU Image
CSB-PA891960LA01HU Image
CSB-PA891960LA01HU Image
Western Blot Positive WB detected in: Hela whole cell lysate, PC-3 whole cell lysate, A549 whole cell lysate All lanes: RAB23 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 27 kDa Observed band size: 27 kDa
CSB-PA891960LA01HU Image
Immunofluorescence staining of U251 cells with CSB-PA891960LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
| Manufacturer: | Cusabio Biotech |
| Preservative: | 0.03% ProClin™ 300 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Ras-related protein Rab-23, RAB23 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant Human Ras-related protein Rab-23 protein (18-234aa) |
| Application: | ELISA, IF, WB |
Description
Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes.
Additional Text
Gene Name
RAB23
Uniprot ID
Q9ULC3
Purification
Protein G purified
Gene ID
51715
Storage Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Antibody Clonality
Polyclonal
SUPPORT
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PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations