SCN11A Antibody

Catalogue Number: CSB-PA924942-CSB

Manufacturer:Cusabio Biotech
Preservative:0.05% Sodium azide
Ph:7.4
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic peptide of Human SCN11A
Application: ELISA, IHC

Description

Description: Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.

Additional Text

Gene Name

Scn11a

Gene ID

11280

Uniprot ID

Q9UI33

Purification

Affinity Purified

Storage Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antibody Clonality

Polyclonal

Specificity

hNaN antibody; NaN antibody; NAV1.9 antibody; Peripheral nerve sodium channel 5 antibody; PN 5 antibody; PN5 antibody; SCN 11A antibody; SCN 12A antibody; Scn11a antibody; SCN12A antibody; SCNBA_HUMAN antibody; Sensory neuron sodium channel 2 antibody; SNS 2 antibody; SNS2 antibody; Sodium channel protein type 11 subunit alpha antibody; Sodium channel protein type XI subunit alpha antibody; Sodium channel voltage gated type XI alpha antibody; Sodium channel voltage gated type XI alpha polypeptide antibody; Sodium channel voltage gated type XI alpha subunit antibody; Sodium channel voltage gated type XII alpha polypeptide antibody; Voltage gated sodium channel Nav1.9 antibody; Voltage gated sodium channel subunit alpha Nav1.9 antibody; Voltage-gated sodium channel subunit alpha Nav1.9 antibody