ANKRD28 Antibody
Catalogue Number: CSB-PA929390-CSB
CSB-PA929390 image
CSB-PA929390 image
CSB-PA929390 Image
CSB-PA929390 image
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA432470(ANKRD26 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
CSB-PA929390 image
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA432470(ANKRD26 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
CSB-PA929390 Image
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: Hela cells, Primary antibody: CSB-PA929390(ANKRD28 Antibody) at dilution 1/1050, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 hours
| Manufacturer: | Cusabio Biotech |
| Preservative: | 0.05% Sodium azide |
| Ph: | 7.4 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide of Human ANKRD28 |
| Application: | ELISA, WB |
Description
Description: Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. ANKRD28 selectively regulated phosphorylation of hnRNP-K at ser284, an effect that was enhanced in vivo by an S1013A/S1017A double mutant, suggesting that ANKRD28 targets PP1 in a regulated manner to dephosphorylate hnRNP-K selectively at ser284.
Additional Text
Uniprot ID
O15084
Purification
Affinity Purified
Gene ID
23243
Gene Name
ANKRD28
Storage Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Antibody Clonality
Polyclonal
Specificity
ANKRD28 antibody; KIAA0379Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A antibody; PP6-ARS-A antibody; Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A antibody; Ankyrin repeat domain-containing protein 28 antibody; Phosphatase interactor targeting protein hnRNP K antibody; PITK antibody
CSB-PA929390 Datasheet
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations