Recombinant Rat Angiopoietin-2 (Angpt2)

Catalogue Number: CSB-YP001707RA-CSB

Manufacturer:Cusabio Biotech
Shelf Life:6 months
Molecular Weight:56.0 kDa
Physical state:Liquid or Lyophilized powder
Type:Other Recombinant Protein
Alias:ANG-2
Host Cell:Yeast
Shipping Condition:Blue Ice
Unit(s): 1 mg, 100 ug, 20 ug
Host name:
Clone:
Isotype:
Immunogen:

Description

Description: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Involved in the regulation of lymphangiogenesis.

Additional Text

Gene Name

ANGPT2

UniProt ID

O35462

Gene ID

89805

Protein Tag

6xHIS Tag

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Price
£1,897.00


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