Recombinant Human Glutamate receptor 3 (GRIA3), partial

Catalogue Number: CSB-YP009900HU-CSB

Manufacturer:Cusabio Biotech
Shelf Life:6 months
Molecular Weight:14 kDa
Physical state:Liquid or Lyophilized powder
Type:Fusion Protein
Alias:AMPA-selective glutamate receptor 3GluR-CGluR-K3Glutamate receptor ionotropic, AMPA 3 ;GluA3
Host Cell:Yeast
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug, 1 mg

Description

Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous syst and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous syst. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Additional Text

Gene Name

GRIA3

Uniprot ID

P42263

Gene ID

2892

OMIN ID

300699

Protein Tag

6xHIS Tag

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Price
£301.00


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