Recombinant Human Potassium channel subfamily K member 2 (KCNK2), partial

Catalogue Number: CSB-YP012070HU-CSB

Manufacturer:Cusabio Biotech
Shelf Life:6 months
Molecular Weight:17.7 kDa
Physical state:Liquid or Lyophilized powder
Type:Fusion Protein
Alias:Outward rectifying potassium channel protein TREK-1 TREK-1 K(+) channel subunit Two pore domain potassium channel TREK-1 Two pore potassium channel TPKC1
Host Cell:Yeast
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug, 1 mg

Description

Description: Ion channel that contributes to passive transmembrane potassium transport (PubMed:23169818). Reversibly converts between a voltage-insensitive potassium leak channel and a voltage-dependent outward rectifying potassium channel in a phosphorylation-dependent manner (PubMed:11319556). In astrocytes, forms mostly heterodimeric potassium channels with KCNK1, with only a minor proportion of functional channels containing homodimeric KCNK2. In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled receptors, such as F2R and CNR1

Additional Text

Gene Name

KCNK2

Uniprot ID

O95069

Gene ID

3776

OMIN ID

603219

Protein Tag

6xHIS Tag

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Price
£301.00


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