Recombinant Human Potassium channel subfamily K member 2(KCNK2),partial
Catalogue Number: CSB-YP012070HU-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 17.7 kDa |
| Physical state: | Liquid or Lyophilized powder |
| Type: | Fusion Protein |
| Alias: | Outward rectifying potassium channel protein TREK-1 TREK-1 K(+) channel subunit Two pore domain potassium channel TREK-1 Two pore potassium channel TPKC1 |
| Host Cell: | Yeast |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 500 ug, 20 ug |
Description
Description: Ion channel that contributes to passive transmembrane potassium transport (PubMed:23169818). Reversibly converts between a voltage-insensitive potassium leak channel and a voltage-dependent outward rectifying potassium channel in a phosphorylation-dependent manner (PubMed:11319556). In astrocytes, forms mostly heterodimeric potassium channels with KCNK1, with only a minor proportion of functional channels containing homodimeric KCNK2. In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled receptors, such as F2R and CNR1
Additional Text
Uniprot ID
O95069
OMIN ID
603219
Protein Tag
6xHIS Tag
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