Recombinant Human Mannose-binding protein C (MBL2)
Catalogue Number: CSB-YP013540HUA4-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 37.1 kda |
| Physical state: | Liquid or Lyophilized powder |
| Type: | Other Recombinant Protein |
| Alias: | MBP-C;Collectin-1;MBP1;Mannan-binding protein;Mannose-binding lectin |
| Host Cell: | Yeast |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 100 ug, 20 ug |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: |
Description
Description: Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA. Upon SARS coronavirus-2/SARS-CoV-2 infection, activates the complement lectin pathway which leads to the inhibition SARS-CoV-2 infection and a reduction of the induced inflammatory response .
Additional Text
Gene ID
4153
Gene Name
MBL2
Uniprot ID
P11226
Protein Tag
6xHIS-SUMOstar™ Tag
Storage Note
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
CSB-YP013540HUA4 MSDS
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