Recombinant Human Sodium/calcium exchanger 1 (SLC8A1), partial

Catalogue Number: CSB-YP021723HU-CSB

Manufacturer:Cusabio Biotech
Shelf Life:6 months
Molecular Weight:27.4 kDa
Physical state:Liquid or Lyophilized powder
Type:Fusion Protein
Alias:Na(+)/Ca(2+)-exchange protein 1 Solute carrier family 8 member 1
Host Cell:Yeast
Shipping Condition:Blue Ice
Unit(s): 1 mg, 100 ug, 20 ug

Description

Description: Mediates the exchange of one Ca2+ ion against three to four Na+ ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca2+ levels and Ca2+-dependent cellular processes (PubMed:1374913, PubMed:11241183, PubMed:1476165). Contributes to Ca2+ transport during excitation-contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca2+ levels due to release of Ca2+ stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca2+ from the cell during the next phase, so that cytoplasmic Ca2+ levels rapidly return to baseline. Required for normal embryonic heart development and the onset of heart contractions.

Additional Text

Gene ID

6546

Gene Name

SLC8A1

Uniprot ID

P32418

OMIN ID

182305

Protein Tag

6xHIS Tag

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Price
£1,586.00


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