Nafamostat Mesylate
Catalogue Number: CV-1002-1-RPE
| Manufacturer: | rPeptide |
| Physical state: | Lyophilized |
| Type: | Protease Inhibitors |
| Shipping Condition: | RT |
| Unit(s): | 10 mg |
Description
Description: A potent and reversible serine protease inhibitor (IC50=0.3-54 uM). Selectively inhibits human tryptase (Ki = 95.3 pM) when employed at low concentrations. Dramatically suppresses pulmonary dysfunction in a rat model and inhibits airway eosinophilic inflammation. Anticoagulant, thrombin inhibitor which attenuates neuronal damage in a transient focal cerebral ischemia model. Also blocks TRPM7 in the absence of extracellular divalent cations. Cell permeable.
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