FK-506
Catalogue Number: CV-1003-2-RPE
| Manufacturer: | rPeptide |
| Physical state: | Lyophilized |
| Type: | Phosphatase Inhibitors |
| Shipping Condition: | RT |
| Unit(s): | 50 mg |
Description
Description: FK-506 induces immunosuppression by inhibiting T cell proliferation. Inhibits FKBP12 and calcineurin (IC50 ca. 1 nM). Reduces neuroinflammation and neurodegeneration in an a-synuclein-based rat model of Parkinson's disease. Increases the rate of axonal regeneration following crush injury in a rat model. Cell permeable.
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