PKC-412 (Midostaurin)

Catalogue Number: CV-1004-1-RPE

Manufacturer:rPeptide
Physical state:Lyophilized
Type:Kinase Inhibitors
Shipping Condition:RT
Unit(s): 1 mg

Description

Description: Pan-specific kinase inhibitor. Selectively induces G1 arrest and apoptosis in Ba/F3 cells expressing mutant FLT3, IC50<10 nM. FLT3 ligand impedes the efficacy of inhibition by PKC-412. Potential therapeutic use in pancreatic cancer. Cell permeable. Active in vivo.