Niclosamide
Catalogue Number: CV-1025-1-RPE
| Manufacturer: | rPeptide |
| Physical state: | Lyophilized |
| Type: | Other Inhibitors |
| Shipping Condition: | RT |
| Unit(s): | 1 g |
Description
Description: Reversibly inhibits mTORC1 signaling and stimulates autophagy. Inhibits activation and nuclear translocation of STAT3 selectively over STAT1 and STAT5. Inhibits transcription of STAT3 target genes and induces cell cycle arrest and apoptosis in cells with constitutively active STAT3. Reverses radioresistance in human lung cancer cells and xenografts.
SUPPORT
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DELIVERY
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