Pridopidine

Catalogue Number: CV-1030-1-RPE

Manufacturer:rPeptide
Physical state:Lyophilized
Type:Biochemicals
Shipping Condition:RT
Unit(s): 5 mg

Description

Description: Potential treatment for Huntington's disease, Parkinson's disease, and schizophrenia. Able to reverse both hypo- and hyperdopaminergia depending on local dopamine concentrations without inducing catalepsy. This was originally attributed to functional dopamine D2 antagonism with fast on/off kinetics ("dopamine stabilizer"). More recent studies have attributed pridopidine's effects to its being a more potent sigma-1 ligand than a D2 ligand. Displays neuroprotective/restorative effects and ameliorates central features of amyotrophic lateral sclerosis pathology in a sigma-1-mediated manner.