7-Cl-O-Nec1
Catalogue Number: CV-1033-2-RPE
| Manufacturer: | rPeptide |
| Physical state: | Pale yellow to off-white powder |
| Type: | Kinase Inhibitors |
| Shipping Condition: | RT |
| Unit(s): | 25 mg |
Description
Description: A necrostatin-1 analog with superior potency, selectivity and metabolic stability at RIP1 inhibition (IC50 = 206 vs 494 nM). Displays greater efficacy at inhibition of necroptosis in Jurkat cells with no non-specific cytotoxicity (100 nM). Ameliorates disease progression in elastase-induced mouse abdominal aortic aneurysm model. Recommended for cellular and in vivo applications over necrostatin-15.
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations