BD1047 dihydrobromide
Catalogue Number: CV-1041-2-RPE
| Manufacturer: | rPeptide |
| Physical state: | Lyophilized |
| Type: | Other Inhibitors |
| Shipping Condition: | RT |
| Unit(s): | 25 mg |
Description
Description: BD1047 is a potent and selective sigma-1 antagonist (IC50's: σ1=0.93 nM, σ2=47 nM). It reduced convulsions, lethality, and locomotor activity induced by cocaine in mouse models. BD1047 attenuated high fat diet-induced peripheral neuropathy in mice. BD1047 displayed antinociceptive effects in several rodent pain models. It also inhibits the β-adrenergic receptor (IC50=145 nM).
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