DNA-PKcs, phosphorylated (Thr2609)
Catalogue Number: D3949-01G-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 10B1 |
| Isotype: | IgG1, kappa |
| Immunogen: | Synthetic modified phospho-peptide corresponding to DNA-PKcs at Thr2609 |
| Application: | ICC, IF, WB |
Description
Description: DNA-protein kinase catalytic subunit (DNA-PKcs) also known as DNA-activated kinase is a nuclear 460-470kD serine threonine kinase involved in double-stranded DNA break repair, VDJ recombination, and transcriptional modulation. DNA-PKcs must bind DNA ends to become active. DNA-PKcs is modified by phosphorylation and has been shown to interact with Ku70/Ku80, KIP, DNA-ligase IV, and XRCC4 proteins. Phosphorylated DNA-PKcs is upregulated after DNA damage.
Additional Text
Purification
Affinity Purified
Modification
Phosphorylated, Thr2609
Antibody Clonality
Monoclonal
D3949-01G Datasheet
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