Catalogue Number: DF7414-AFF
Manufacturer: | Affinity Biosciences Ltd |
Shelf Life: | 12 months |
Preservative: | Azide |
Ph: | 7.4 |
Physical state: | Liquid |
Type: | Polyclonal Primary Antibody - Unconjugated |
Alias: | ZEB1 AREB6 TCF8 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul, 200 ul |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | A synthesized peptide derived from human ZEB1, corresponding to a region within the internal amino acids. |
Application: | ICC, IF, WB, IHC-Fr, IHC, pELISA |
Description: Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
ZEB1
P37275
1 mg/ml
Affinity Purified
6935
Polyclonal
124kDa,180kDa