Anti-mutated Calreticulin / CALR (Hu) from Mouse (CAL2)

Catalogue Number: DIA-CAL-100-DIA

Manufacturer:Dianova
Preservative:0.05% Sodium azide
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CALR;Calreticulin;CTR;RO;CC1qR;HACBP;grp60;CRTC;CRP55;Calregulin;Sicca Syndrome Antigen A;Autoantigen Ro;Endoplasmic reticulum resident protein 60;CRT;ERp60
Shipping Condition:RT
Storage Condition:2-8°C
Unit(s): 100 ul
Host name: Mouse
Clone: CAL2
Isotype: IgG2a
Immunogen: C-neoterminus of mutated CALR
Application: ICC, IHC

Description

Description: CAL2 labels the megakaryocytes in myeloproliferative neoplasms (essential thrombocythaemia (ET) and primary myelofibrosis (PMF)) with CALR mutation and enables to distinguish ET and PMF with CALR mutation from polycythemia vera (PV), from CALR mutation negative ET and PMF and from reactive bone marrow. Staining pattern: Cytoplasmic staining of megakaryocytes harboring CALR mutation. The CAL2 IHC assay indicates absence of CALR mutation when all megakaryocytes remain unlabeled.

Additional Text

Gene ID

811

Gene Name

CALR

Uniprot ID

P27797

Purification

Purified

Antibody Clonality

Monoclonal