Anti-mutated Calreticulin / CALR (Hu) from Mouse (CAL2)
Catalogue Number: DIA-CAL-250-DIA
| Manufacturer: | Dianova |
| Preservative: | 0.05% Sodium azide |
| Physical state: | Lyophilized |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | CALR;Calreticulin;CTR;RO;CC1qR;HACBP;grp60;CRTC;CRP55;Calregulin;Sicca Syndrome Antigen A;Autoantigen Ro;Endoplasmic reticulum resident protein 60;CRT;ERp60 |
| Shipping Condition: | RT |
| Storage Condition: | 2-8°C |
| Unit(s): | 250 ul |
| Host name: | Mouse |
| Clone: | CAL2 |
| Isotype: | IgG2a |
| Immunogen: | C-neoterminus of mutated CALR |
| Application: | ICC, IHC |
Description
Description: CAL2 labels the megakaryocytes in myeloproliferative neoplasms (essential thrombocythaemia (ET) and primary myelofibrosis (PMF)) with CALR mutation and enables to distinguish ET and PMF with CALR mutation from polycythemia vera (PV), from CALR mutation negative ET and PMF and from reactive bone marrow. Staining pattern: Cytoplasmic staining of megakaryocytes harboring CALR mutation. The CAL2 IHC assay indicates absence of CALR mutation when all megakaryocytes remain unlabeled.
Additional Text
Gene ID
811
Gene Name
CALR
Uniprot ID
P27797
Purification
Purified
Antibody Clonality
Monoclonal
DIA-CAL-250 Technical Notes
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