Biotinylated Human DLL4 Protein (DLL-HM404B)
Catalogue Number: DLL-HM404B-KAT
DLL-HM404B Image
DLL-HM404B Image
DLL-HM404B Image
DLL-HM404B Image
The purity of Biotinylated Human DLL4 is greater than 95% as determined by SEC-HPLC.
DLL-HM404B Image
Biotinylated Human DLL4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
DLL-HM404B Image
Immobilized Biotinylated Human DLL4, His Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-DLL4 Antibody, hFc Tag with the EC50 of 4.1ng/ml determined by ELISA (QC Test).
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 55.7 kDa. Due to glycosylation, the protein migrates to 62-68 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Protein - Conjugated |
| Alias: | DLL-4; MGC126344; notch ligand DLL4; Delta4; Delta-like 4 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate.
Additional Text
Gene ID
54567
Gene Name
DLL4
Uniprot ID
Q9NR61
Protein Tag
HIS-AviTag™
Short Description
Recombinant Biotinylated Human DLL4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser27-Pro524.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
Immobilized Anti-DLL4 Antibody, hFc Tag at 1Oeg/ml (100Oel/Well) on the plate. Dose response curve for Biotinylated Human DLL4, His Tag with the EC50 of 0.33Oeg/ml determined by ELISA. See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
DLL-HM404B Datasheet
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