Catalogue Number: DR3-HM401B-KAT
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 26.40 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
| Physical state: | Liquid |
| Type: | Protein - Conjugated |
| Alias: | APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; TNFRSF25; LARD; TR3; TRAMP; WSL-LR |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug, 500 ug |
Description: Death Receptor 3 (DR3), also known as TNFRSF25, TRAMP, LARD, or WSL-1, is a death-domain-containing TNF-family receptor that, like its closest paralog TNFR1, binds the adaptor molecule TRADD through its cytoplasmic death domain. TRADD recruitment endows DR3 with dual-signaling capability to activate NF-κB and MAP-kinase signaling or alternatively trigger caspase activation and programmed cell death.
HIS-AviTag™
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
AAI17190.1
Less than 1 EU per µg by the LAL method.
Recombinant Biotinylated Human DR3/TNFRSF25 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Gln25-Gln199.