XRCC4 Monoclonal Antibody

Catalogue Number: E-AB-22044-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Preservative:0.02% Sodium azide
Ph:7.4
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 120 ul, 20 ul, 60 ul, 200 ul
Host name: Mouse
Clone: Clone:8K2
Isotype: IgG
Immunogen: Synthetic Peptide
Application: IF, IHC-P, IP, WB, IHC

Description

Description: Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Additional Text

Gene ID

7518

Gene Name

XRCC4

Uniprot ID

Q13426

Purification

Protein A purified

Antibody Clonality

Monoclonal

Concentration

1 mg/ml

Specificity

DNA double strand break repair and V(D)J recombination protein XRCC4;DNA repair protein XRCC4;SSMED;X ray repair complementing defective repair in Chinese hamster cells 4;X ray repair cross complementing 4;X ray repair cross complementing protein 4;X-ray repair cross-complementing protein 4;XRCC 4;XRCC4;XRCC4

Storage Note

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Price
£240.00


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