Cleaved-CASP3 p17 (D175) Polyclonal Antibody

Catalogue Number: E-AB-30004-ELA

Manufacturer:	Elabscience
Shelf Life:	12 months
Preservative:	0.02% Sodium azide
Ph:	7.4
Type:	Polyclonal Primary Antibody - Unconjugated
Shipping Condition:	Blue Ice
Unit(s):	120 ul, 20 ul, 60 ul, 200 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Synthesized peptide derived from the Internal region of human Caspase-3 p17
Application:	IF, IHC-P, WB, IHC

Overview
Datasheets

Description

Description: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.

Additional Text

Gene Name

CASP3

Gene ID

836

Uniprot ID

P42574

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Concentration

1 mg/ml

Specificity

A830040C14Rik;Apopain;CASP-3;CASP3;CASP3;Casp3a;Caspase 3;Caspase 3;apoptosis-related cysteine peptidase;Caspase 3;apoptosis-related cysteine protease;Caspase 3;apoptosis-related cysteine protease a;Caspase-3 subunit p12;CC3;CPP-32;CPP32;CPP32B;Cysteine protease CPP32;EC 3.4.22.56;LICE;mldy;OTTHUMP00000165052;OTTHUMP00000165053;OTTHUMP00000165054;PARP cleavage protease;Procaspase3;Protein Yama;SCA 1;SCA-1;SREBP cleavage activity 1;Yama

Storage Note

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

E-AB-30004 Protocol

E-AB-30004 MSDS

Price

£240.00

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