Cleaved-PARP1 (D214) Polyclonal Antibody

Catalogue Number: E-AB-30080-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Preservative:0.02% Sodium azide
Ph:7.4
Type:Polyclonal Primary Antibody - Unconjugated
Alias:ADP-ribosyltransferase diphtheria toxin-like 1;ADPRT 1;ADPRT;ADPRT1;APOPAIN;ARTD1;NAD(+) ADP-ribosyltransferase 1;PARP;PARP-1;PARP1;PARP1;Poly [ADP-ribose] polymerase 1;Poly ADP ribose polymerase 1;Poly[ADP-ribose] synthase 1;PPOL;SCA1
Shipping Condition:Blue Ice
Unit(s): 120 ul, 20 ul, 60 ul, 200 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthesized peptide derived from the Internal region of human PARP-1
Application: IF, IHC-P, WB, IHC

Description

Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Additional Text

Gene Name

PARP1

Uniprot ID

P09874

Gene ID

142

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Concentration

1 mg/ml

Storage Note

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Price
£240.00


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