RUNX2 Polyclonal Antibody
Catalogue Number: E-AB-30103-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.02% Sodium azide |
| Ph: | 7.4 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 120 ul, 20 ul, 60 ul, 200 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthesized peptide derived from the Internal region of human RUNX2. |
| Application: | IF, WB |
Description
Description: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters (By similarity). Inhibits MYST4-dependent transcriptional activation.
Additional Text
Gene Name
RUNX2
Gene ID
860
Uniprot ID
Q13950
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Concentration
1 mg/ml
Specificity
Acute myeloid leukemia 3 protein;Alpha subunit 1;AML3;CBF alpha 1;CBF-alpha-1;CBFA1;CCD;CCD1;Cleidocranial dysplasia 1;Core binding factor;Core binding factor runt domain alpha subunit 1;Core binding factor subunit alpha 1;Core-binding factor subunit alpha-1;MGC120022;MGC120023;Oncogene AML 3;Oncogene AML-3;OSF 2;OSF-2;OSF2;Osteoblast specific transcription factor 2;Osteoblast-specific transcription factor 2;OTTHUMP00000016533;PEA2 alpha A;PEA2-alpha A;PEA2aA;PEBP2 alpha A;PEBP2-alpha A;PEBP2A1;PEBP2A2;PEBP2aA;PEBP2aA1;Polyomavirus enhancer binding protein 2 alpha A subunit;Polyomavirus enhancer-binding protein 2 alpha A subunit;Runt domain;Runt related transcription factor 2;Runt-related transcription factor 2;RUNX2;RUNX2;SL3 3 enhancer factor 1 alpha A subunit;SL3-3 enhancer factor 1 alpha A subunit;SL3/AKV core binding factor alpha A subunit;SL3/AKV core-binding factor alpha A subunit
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-30103 Protocol
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DELIVERY
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