CD284 Polyclonal Antibody

Catalogue Number: E-AB-30816-ELA

Manufacturer:	Elabscience
Shelf Life:	12 months
Preservative:	0.02% Sodium azide
Ph:	7.4
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	ARMD10;CD284;CD284 antigen;Homolog of Drosophila toll;hToll;TLR 4;TLR4;TLR4;TOLL;Toll like receptor 4;Toll-like receptor 4
Shipping Condition:	Blue Ice
Unit(s):	120 ul, 20 ul, 60 ul, 200 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Synthesized peptide derived from the Internal region of human CD284.
Application:	IF, IHC-P, WB, IHC

Overview
Datasheets

Description

Description: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.

Additional Text

Gene Name

TLR4

Gene ID

7099

Uniprot ID

O00206

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Concentration

1 mg/ml

Storage Note

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

E-AB-30816 Protocol

E-AB-30816 MSDS

Price

£240.00

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