SMG7 Polyclonal Antibody

Catalogue Number: E-AB-32926-ELA

Manufacturer:	Elabscience
Shelf Life:	12 months
Preservative:	0.02% Sodium azide
Type:	Polyclonal Primary Antibody - Unconjugated
Shipping Condition:	Blue Ice
Unit(s):	120 ul, 20 ul, 200 ul, 60 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Synthesized peptide derived from the Internal region of human SMG7
Application:	IF, IHC-P, WB, IHC

Overview
Datasheets

Description

Description: This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.SMG7 (SMG7, Nonsense Mediated MRNA Decay Factor) is a Protein Coding gene. Among its related pathways are Gene Expression and Viral mRNA Translation. GO annotations related to this gene include protein phosphatase 2A binding. An important paralog of this gene is SMG6.

Additional Text

Gene ID

9887

Gene Name

SMG7

Uniprot ID

Q92540

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Concentration

1 mg/ml

Specificity

breast cancer-associated antigen SGA-56M;C1orf16;EST1 like protein C;EST1 telomerase component homolog C;EST1-like protein C;EST1C;ever shorter telomeres 1C;FLJ23717;hSMG-7;nonsense mediated mRNA decay factor (C. elegans);Protein SMG7;SGA56M;SMG 7;SMG-7 homolog;Smg7;SMG7

Storage Note

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

E-AB-32926 Protocol

E-AB-32926 MSDS

Price

£240.00

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