Catalogue Number: E-AB-60188-ELA
Western blot analysis of extracts of various cell lines with BCL10 Polyclonal Antibody
Western blot analysis of extracts from normal (control) and BCL10 knockout (KO) HeLa cells, using BCL10 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts from normal (control) and BCL10 knockout (KO) HeLa cells using BCL10 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using BCL10 Polyclonal Antibody at dilution of 1:1000.
|Preservative:||0.02% Sodium azide|
|Type:||Polyclonal Primary Antibody - Unconjugated|
|Shipping Condition:||Blue Ice|
|Unit(s):||120 ul, 200 ul, 60 ul|
|Immunogen:||Recombinant fusion protein of human BCL10 (NP_003912.1).|
Description: This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.
AI132454,B cell CLL/lymphoma 10,B cell lymphoma/leukemia10,B-cell CLL/lymphoma 10,B-cell leukemia/lymphoma 10,B-cell lymphoma/leukemia 10,Bcl 10,Bcl-10,Bcl10,BCL10,c E10,c-E10,C81403,CARD containing apoptotic signaling protein,CARD containing molecule enhancing NF kappa B,CARD containing molecule enhancing NF kB,CARD containing molecule enhancing NF-kB,CARD containing molecule enhancing NFkB,CARD containing proapoptotic protein,CARD like apoptotic protein,CARD-containing apoptotic signaling protein,CARD-containing molecule enhancing NF-kappa-B,CARD-containing proapoptotic protein,CARD-like apoptotic protein,CARMEN,Caspase recruiting domain containing protein,caspase-recruiting domain-containing protein,cCARMEN,cE 10,cE10,CED 3/ICH 1 prodomain homologous E10 like regulator,CED-3/ICH-1 prodomain homologous E10-like regulator,CED3/ICH1 prodomain homologous E10 like regulator,Cellular E10,Cellular homolog of vCARMEN,Cellular-E10,CIPER,CLAP,hCLAP,Mammalian CARD containing adapter molecule E10,Mammalian CARD-containing adapter molecule E10,mE 10,mE10,R-RCD1