(KO Validated) CCND3 Polyclonal Antibody

Catalogue Number: E-AB-63262-ELA

Manufacturer:	Elabscience
Preservative:	0.02% Sodium azide
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	CCND3,cyclin D3,Cyclin D3
Shipping Condition:	Blue Ice
Unit(s):	120 ul, 200 ul, 60 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Recombinant fusion protein of human CCND3 (NP_001751.1).
Application:	WB

Overview
Datasheets

Description

Description: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.

Additional Text

Concentration

1 mg/ml

Gene ID

896

Gene Name

CCND3

Uniprot ID

P30281

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Store at -20°C. Avoid freeze / thaw cycles.

E-AB-63262 Protocol

Price

£231.00

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Quantity
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