Catalogue Number: E-AB-70079-ELA
| Manufacturer: | Elabscience |
| Preservative: | 0.02% Sodium azide |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | ARMD10,CD284,CD284 antigen,Homolog of Drosophila toll,hToll,TLR 4,TLR4,TLR4,TOLL,Toll like receptor 4,Toll-like receptor 4 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 120 ul, 200 ul, 60 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse TLR4 |
| Application: | IHC |
Description: TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
1.1 mg/ml
Affinity Purified
O00206, Q9QUK6, Q9QX05
Polyclonal
Store at -20°C. Avoid freeze / thaw cycles.